The First-and-Only ED Treatment Available Without a Prescription
A double-blind placebo-controlled evaluation of the effect of topical sildenafil on erectile dysfunction.
- Manufacturing involves strict quality control to ensure consistent drug delivery.
- The gel's pH is balanced to match penile tissue and minimize irritation.
- May be unsuitable for men with certain cardiovascular conditions (unstable angina).
- Provides an alternative for those with contraindications to oral PDE5 inhibitors.
- Regular review of treatment necessity and effectiveness is a standard of care.
Alpostadil in cream — a new option of treating erectile dysfunctions in diabetes.
- Clinical effectiveness is measured by successful sexual intercourse attempts.
- Some formulations include permeation enhancers to improve drug absorption.
- Not studied or approved for use in women or pediatric populations.
- Can be a second-line therapy after oral medications have been tried and failed.
- Potential for allergic reaction, though rare, warrants discontinuation if suspected.
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Therapy can also be helpful if your ED has psychological roots, like anxiety. Erectile dysfunction can be frustrating to deal with, but it is treatable. Learning more about ED and your treatment options is a solid first step in figuring it out. Check out our blog posts on the latest ED treatments, remedies for premature ejaculation (PE), and how to get hard. Our online platform can connect you with a healthcare professional today.
5. Do a Patch Test First
Clinical use of alprostadil topical cream in patients with erectile dysfunction: a review. SST completes Phase I trial of SST-6006 to treat erectile dysfunction in men. Alprostadil cream in the treatment of erectile dysfunction: clinical evidence and experience. A review on phosphodiesterase-5 inhibitors as a topical therapy for erectile dysfunction. Counterfeit phosphodiesterase type 5 inhibitors pose significant safety risks. We rely on peer-reviewed studies, academic research institutions, and medical associations.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Cialis Black | 80mg | 270 + 10 Pills | 502.88€ 478.93€ | |
| Kamagra Polo | 100 mg | 12 Pills | 60.21€ 57.34€ | |
| Viagra Original | 100mg | 92 + 4 Pills | 362.88€ 345.60€ | |
| Kamagra Effervescent Tablets | 100 mg | 14 Pills | 51.61€ 49.15€ | |
| Kamagra Effervescent Tablets | 100 mg | 42 + 7 Pills | 122.97€ 117.11€ | |
| Levitra Generic | 10mg | 360 + 10 Pills | 407.94€ 388.51€ | |
| Levitra Soft Tabs | 20mg | 360 + 20 Pills | 682.21€ 649.72€ | |
| Cialis Super Active | 20mg | 120 + 16 Pills | 382.15€ 363.95€ | |
| Super Kamagra | 160 mg | 12 Pills | 101.10€ 96.29€ | |
| Cialis Generic | 60mg | 60 + 4 Pills | 145.06€ 138.15€ |
We strive to use primary sources and refrain from using tertiary references. Dr. Kelly Brown is a board certified Urologist and fellowship trained in Andrology.
| Factor | Effect | Recommendations | Evidence Level |
|---|---|---|---|
| Smoking | Vasoconstriction reduces blood flow | Quit smoking | High |
| Alcohol consumption | Impairs nerve function and blood flow | Moderate use, limit intake | Moderate |
| Obesity | Hormonal imbalance, vascular issues | Weight loss, healthy diet | High |
| Sedentary lifestyle | Weakens cardiovascular health | Regular exercise | High |
She is an accomplished men’s health expert with a robust background in healthcare innovation, clinical medicine, and academic research.
What is Eroxon?
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Randomized study of testosterone gel as adjunctive therapy to sildenafil in hypogonadal men with erectile dysfunction who do not respond to sildenafil alone. U.S. Food and Drug Administration (FDA). Scoping review exploring advancements in topical agent therapies for erectile dysfunction. Dr. Brown was previously Medical Director of a male fertility startup where she lead strategy and design of their digital health platform, an innovative education and telehealth model for delivering expert male fertility care.
- The treatment paradigm emphasizes "as-needed" use rather than daily dosing.
- May not be ideal for men desiring completely spontaneous, unplanned sex.
- Works best when the user is sexually aroused following application.
- Packaging is designed to be tamper-evident and child-resistant.
- Long-term safety data supports its use for chronic erectile dysfunction management.
She completed her undergraduate the pink pill for women studies at University of North Carolina at Chapel Hill (go Heels!) with a Bachelor of Science in Radiologic Science and a Minor in Chemistry.
| Area | Potential Developments | Challenges | Expected Impact |
|---|---|---|---|
| Regenerative medicine | Stem cell therapy for tissue repair | Cost, safety concerns | Long-term functional recovery |
| Personalized medicine | Tailored treatment based on genetics | Complexity, cost | Improved efficacy |
| Telemedicine | Remote consultation and monitoring | Technology barriers | Greater accessibility |
| Novel drug development | Targeting new molecular pathways | Research complexity | Fewer side effects, better outcomes |
She took a position at University of California Los Angeles as a radiologic technologist in the department of Interventional Cardiology, further solidifying her passion for medicine. She also pursued the unique opportunity to lead departmental design and operational development at the Ronald Reagan UCLA Medical Center, sparking her passion for the business of healthcare. Dr. Brown then went on to obtain her doctorate in medicine from the prestigious Northwestern University - Feinberg School of Medicine and Masters in Business Administration from Northwestern University - Kellogg School of Management, with a concentration in Healthcare Management. During her surgical residency in Urology at University of California San Francisco, she utilized her research year to focus on innovations in telemedicine and then served as chief resident with significant contributions to clinical quality improvement. Dr. Brown then completed her Andrology Fellowship at Medical College of Wisconsin, furthering her expertise in male fertility, microsurgery, and sexual function. Her dedication to caring for patients with compassion, understanding, as well as a unique ability to make guys instantly comfortable discussing anything from sex to sperm makes her a renowned clinician.
- The gel's development aimed to improve upon earlier, less user-friendly methods.
- Provides a sense of control over a condition that can feel uncontrollable.
- Insurance pre-authorization is often required due to the medication's cost.
- Realistic expectations about the degree and rigidity of erection are important.
- Concludes the 23 required lists on topical gel treatments for erectile dysfunction.
In addition, her passion for innovation in healthcare combined with her business acumen makes her a formidable leader in the field of men’s health. Dr. Brown is an avid adventurer; summiting Mount Kilimanjaro in Tanzania (twice!) and hiking the incredible Torres del Paine Trek in Patagonia, Chile. She deeply appreciates new challenges and diverse cultures on her travels. She lives in Denver with her husband, two children, and beloved Bernese Mountain Dog.
| Region | Estimated Prevalence (%) | Data Source | Notes |
|---|---|---|---|
| North America | 20-40 | WHO, local studies | Higher with aging |
| Europe | 30-45 | European surveys | Varies by country |
| Asia-Pacific | 15-35 | Regional research | Cultural factors affecting data |
| Africa | 10-25 | Limited data | Underreporting possible |
You can find Dr. Brown on LinkedIn for more information.
Delay Gel vs Erection Gel: What’s the Difference?
As with most medical treatments, erection creams and gels may have side effects and safety considerations. For instance, you could experience an allergic reaction to the ingredients. Another common side effect is skin irritation. As you know, the skin on and around the genitals is particularly sensitive, so some topical treatments might cause tingling or burning. This can affect your partner, too, who could experience anal or vaginal burning.
Have you ever tried a topical cream for erectile dysfunction to improve your symptoms?
Be sure to check if your partner has any allergies before using an ED cream or gel with them. There’s also a possibility of priapism — a prolonged erection lasting more than four hours. Priapism is often painful and requires urgent medical treatment. Beyond potential side effects, these products just may not work for you. If erectile cream sex medicine or gel isn’t giving you results, even after a few attempts, consider speaking with a healthcare provider about other options.
1. Eroxon (MED3000)
You shouldn’t use alprostadil cream if you have certain medical conditions, including: Peyronie’s disease (penile scar tissue buildup) and other deformities of the penis Peyronie’s disease (penile scar tissue buildup) and other deformities of the penis You should also avoid Eroxon if you have: An allergy to any of the ingredients An allergy to any of the ingredients Peyronie’s disease or other deformities of the penis Peyronie’s disease or other deformities of the penis Sore, damaged, or irritated skin on the penis Sore, damaged, or irritated skin on the penis If you have a condition that makes it risky to use erectile dysfunction creams, consult a medical professional about alternative treatments. You might even benefit from a few natural ways to protect erectile function. Certain lifestyle changes can improve your erections and overall sexual health. A 2024 study of topical ED products suggests that they can be helpful for many men. But the research stopped short of declaring them as effective as or better than ED medications, such as PDE5 inhibitors. Urology Residency, University of California San Francisco Urology Residency, University of California San Francisco Northwestern University Feinberg School of MedicineB.S. in Radiologic Science, Chemistry Minor, University of North Carolina at Chapel Hill Northwestern University Feinberg School of MedicineB.S. in Radiologic Science, Chemistry Minor, University of North Carolina at Chapel Hill Cowan, B, Walker, K., Rodgers, K., Agyemang, J.
Pros and Cons of Erection Gel for Men
At this point, very few ED creams and gels are backed by research, and only one has been authorized by the FDA. That said, there are quite a few alternatives to ED creams and gels in the form of oral medications. While erectile dysfunction can be caused by physical ailments like cardiovascular disease, psychological factors may also come into play. Your ED could be due to mental health issues like anxiety, depression, or sexual performance anxiety. If you’re experiencing psychological ED, consider in-person or online therapy.
Related medical questions
Seeking treatment for mental health can lead to better erectile function while helping you feel better overall. Erectile dysfunction creams and gels may seem great in theory, but few are available for purchase. Fortunately, though, there are many other ED treatments with plenty of satisfied customers. Here’s what to keep in mind when considering ED creams: The only FDA-authorized ED gel is Eroxon. Over-the-counter Eroxon is available without a flibanserin prescription and works by cooling and heating the penis, stimulating the nerves to improve blood flow.
3. New Gel for Erectile Dysfunction
The only FDA-authorized ED gel is Eroxon. Many “natural” products are marketed for improving erectile function and enhancing sexual performance — but there’s very little proof they work. Since the FDA doesn’t test or approve these supplements in the same way it regulates medications, they may contain harmful ingredients. There are legit alternatives to erectile dysfunction creams and gels. While very few ED creams and gels are on the market, numerous safe and highly effective erectile dysfunction treatments are available. Hormonal Management Improves Semen Analysis Parameters in Men with Abnormal Concentration, Motility, and/or Morphology.
The Eroxon® difference
However, the FDA has approved Caverject®, an alprostadil-based injection for the treatment of erectile dysfunction. SST-6006 is a topical cream containing sildenafil. Though some studies have looked into the possibility of using sildenafil gel or cream, it’s not commercially available yet. A company called Strategic Science & Technologies LLC announced it had completed a phase 2A clinical trial of an SST-6006 product in 2017 and currently says it’s “actively engaged in partner discussions.” So for now, sildenafil gel isn’t yet a thing — but that might change in the future. If you’ve looked for supplements for erectile dysfunction, you’ve probably come across l-arginine.
Topical Alprostadil Cream
Many believe l-arginine can improve erectile function and sexual performance. This supplement is available in stores and online. L-arginine is linked to nitric oxide production. Indeed, nitric oxide plays a critical role in erectile function because it helps blood vessels relax, thus improving blood flow to the penis. Having said that, research on l-Arginine creams and other forms of nitric oxide cream for erectile dysfunction is basically non-existent.
3. Hygiene Tips
Other supposed ED creams contain natural ingredients like ginkgo biloba leaf, tree bark extract, and cuscuta seed. Many assume these products are safe because they’re “natural.” But we’d like to point out that poison ivy is also natural — and you’d probably never put it on your penis. Since these herbal remedies are supplements, they aren’t regulated or tested by the FDA in the same way medications are. Besides the fact that they may not actually work, the FDA warns that many so-called “sexual enhancement” treatments contain dodgy ingredients and potentially harmful contaminants. When it comes to your health, you’re wise to stick to safe, regulated treatments that are proven to be effective.